Using individualized opening pressure to determine the optimal setting of an adjustable proGAV shunt in treatment of hydrocephalus in infants

Childs Nerv Syst. 2015 Aug;31(8):1267-71. doi: 10.1007/s00381-015-2795-2. Epub 2015 Jul 5.

Abstract

Introduction: The aim of the study was to describe the authors' experiences with the adjustable gravitational proGAV shunt system in treating infants' hydrocephalus.

Patients and methods: The proGAV was implanted in 29 infants (11 boys and 18 girls, median age 9 months) with hydrocephalus of various origins between January 2010 and June 2014. The opening pressure was chosen based on the intraventricular pressure which was measured during operation, and a gravitational unit with a fixed opening pressure (15 cm H2O) was selected.

Result: Regular clinical follow up ranged from 6 to 36 months, with a mean follow-up time of 15.7 ± 7.9 months. Five of these patients (17.2%) underwent shunt revision because of malfunction, including two infections (6.9%), two shunt exposed (6.9%), and one proximal catheter occlusion (3.4%). For readjustment in 10 infants, the opening pressure was changed at least once during the follow-up period.

Conclusion: The proGAV is efficacious in the treatment of hydrocephalus in infants. This individual selection of the opening pressures makes it probable that a better match of chosen opening pressure and actual hydraulic requirements of the patient might occur.

MeSH terms

  • Female
  • Gravitation*
  • Humans
  • Hydrocephalus / surgery*
  • Infant
  • Longitudinal Studies
  • Male
  • Pressure*
  • Prostheses and Implants
  • Treatment Outcome
  • Ventriculoperitoneal Shunt / methods*