Ca(II) -catalyzed alkenylation of alcohols with vinylboronic acids

David Leboeuf; Marc Presset; Bastien Michelet; Christophe Bour; Sophie Bezzenine-Lafollée; Vincent Gandon

doi:10.1002/chem.201501677

Ca(II) -catalyzed alkenylation of alcohols with vinylboronic acids

Chemistry. 2015 Jul 27;21(31):11001-5. doi: 10.1002/chem.201501677. Epub 2015 Jul 1.

Authors

David Leboeuf¹, Marc Presset¹, Bastien Michelet¹, Christophe Bour¹, Sophie Bezzenine-Lafollée¹, Vincent Gandon²

Affiliations

¹ ICMMO (UMR CNRS 8182), Université Paris-Sud, Bâtiment 420, 91405 Orsay cedex (France).
² ICMMO (UMR CNRS 8182), Université Paris-Sud, Bâtiment 420, 91405 Orsay cedex (France). vincent.gandon@u-psud.fr.

PMID: 26133924
DOI: 10.1002/chem.201501677

Abstract

Direct alkenylation of a variety of alcohols with vinylboronic acids has been accomplished using the air-stable calcium(II) complex Ca(NTf2 )2 under mild conditions with short reaction times. For reluctant transformations, an ammonium salt was used as an additive to circumvent the reactivity issue.

Keywords: alcohol; calcium; cross-coupling; homogeneous catalysis; vinylboronic acid.