Feasibility and Safety of Urgent Laparoscopic Cholecystectomy for Acute Cholecystitis After 4 Days from Symptom Onset

J Gastrointest Surg. 2015 Oct;19(10):1787-93. doi: 10.1007/s11605-015-2878-0. Epub 2015 Jul 1.

Abstract

Background: It is preferable to perform laparoscopic cholecystectomy for acute cholecystitis in the acute phase, within 72 h of symptom onset. The feasibility and safety of performing urgent laparoscopic cholecystectomy in the late phase (4-7 days after symptom onset) are unclear. The aim of this study was to clarify the feasibility and safety of late phase urgent laparoscopic cholecystectomy.

Methods: Between 2005 and 2014, 233 patients underwent urgent laparoscopic cholecystectomy for acute cholecystitis within 7 days. We compared clinical features and perioperative outcomes between patients who underwent laparoscopic cholecystectomy within 3 days (early phase group) and 4-7 days after symptom onset (late phase group).

Results: There were 193 patients in the early phase group and 40 patients in the late-phase group. Performing laparoscopic cholecystectomy in the late phase did not influence operation time, postoperative complications, or postoperative hospital stay. The rate of conversion to open surgery and blood loss were slightly higher in the late-phase group (8 % and 140 ml) compared with the early phase group (3 % and 69 ml) but were still acceptable.

Conclusions: Late phase urgent laparoscopic cholecystectomy for acute cholecystitis was feasible and safe.

Keywords: Acute cholecystitis; Blood loss; Emergency operation; Laparoscopic cholecystectomy; Late phase.

MeSH terms

  • Cholecystectomy, Laparoscopic / methods*
  • Cholecystitis, Acute / surgery*
  • Feasibility Studies
  • Female
  • Humans
  • Length of Stay / trends
  • Male
  • Middle Aged
  • Operative Time
  • Postoperative Period