Risk factors associated with falls in elderly patients with type 2 diabetes

J Diabetes Complications. 2015 Sep-Oct;29(7):898-902. doi: 10.1016/j.jdiacomp.2015.05.016. Epub 2015 Jun 1.

Abstract

Aims: This study investigated risk factors of falls in elderly patients with type 2 diabetes mellitus.

Methods: A total of 211 patients aged ≧60years (168 diabetic patients and 43 non-diabetic control subjects) were studied. Factors associated with falls in the past year were retrospectively examined using multiple logistic regression analysis.

Results: The prevalence of patients who had a history of falls in the past year was twice as high as in diabetic patients compared in control subjects (36.9% vs. 18.6%, P<0.05). When diabetic patients were exclusively analyzed, the presence of any level of hypoglycemia and the Timed Up and Go test (TUG) scores correlated with patients' falls. The presence of hypoglycemia (OR 3.62, 95% CI: 1.242-10.534, P=0.018), cognitive impairment (OR 3.63, 95% CI: 1.227-10.727, P=0.020), and high Fall Risk Index scores (OR 1.2, 95% CI: 1.010-1.425, P=0.039) was independently correlated with the presence of multiple falls. When the diabetic patients were divided into three groups according to the frequency of hypoglycemia episodes, the prevalence of falls increased as the frequency of hypoglycemia increased.

Conclusion: Hypoglycemia was a risk factor of falls in elderly type 2 diabetic patients.

Keywords: Elderly type 2 diabetes; Falls; Frailty; Hypoglycemia; Impaired balance; Sarcopenia.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accidental Falls / statistics & numerical data*
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Blood Glucose / analysis
  • Chi-Square Distribution
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / physiopathology
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / therapy
  • Female
  • Geriatric Assessment
  • Humans
  • Hypoglycemia / epidemiology*
  • Hypoglycemia / physiopathology
  • Male
  • Middle Aged
  • Prevalence
  • Prognosis
  • Reference Values
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution
  • Statistics, Nonparametric

Substances

  • Blood Glucose