New therapies for relapsed castration-resistant prostate cancer based on peptide analogs of hypothalamic hormones

Andrew V Schally; Norman L Block; Ferenc G Rick

doi:10.4103/1008-682X.152819

New therapies for relapsed castration-resistant prostate cancer based on peptide analogs of hypothalamic hormones

Asian J Androl. 2015 Nov-Dec;17(6):925-8. doi: 10.4103/1008-682X.152819.

Authors

Andrew V Schally¹, Norman L Block, Ferenc G Rick

Affiliation

¹ Veterans Affairs Medical Center and South Florida Veterans Affairs Foundation for Research and Education, Miami, FL 33125; Department of Pathology; Department of Medicine, Division of Hematology/Oncology; Department of Medicine, Division of Endocrinology; Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Abstract

It is a pleasure to contribute our presentation at the International Prostate Forum of the Annual Meeting of the American Urological Association (AUA) to this special issue of the Asian Journal of Andrology.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Androgen Antagonists / therapeutic use
Carcinoma / drug therapy*
Doxorubicin / analogs & derivatives
Doxorubicin / therapeutic use
Gonadotropin-Releasing Hormone / agonists*
Gonadotropin-Releasing Hormone / analogs & derivatives
Gonadotropin-Releasing Hormone / antagonists & inhibitors
Gonadotropin-Releasing Hormone / therapeutic use
Humans
Hypothalamic Hormones*
Leuprolide / therapeutic use
Male
Oligopeptides / therapeutic use
Peptides
Prostatic Neoplasms, Castration-Resistant / drug therapy*

Substances

Androgen Antagonists
Hypothalamic Hormones
Oligopeptides
Peptides
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide
LHRH, lysine(6)-doxorubicin
Gonadotropin-Releasing Hormone
Doxorubicin
Leuprolide