Go with your gut: microbiota meet microglia

Kira Irving Mosher; Tony Wyss-Coray

doi:10.1038/nn.4051

Go with your gut: microbiota meet microglia

Nat Neurosci. 2015 Jul;18(7):930-1. doi: 10.1038/nn.4051.

Authors

Kira Irving Mosher¹, Tony Wyss-Coray²

Affiliations

¹ Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.
² 1] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA [2] Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, USA.

PMID: 26108718
PMCID: PMC4867548
DOI: 10.1038/nn.4051

Abstract

Discovering the environmental factors that control microglia is key to understanding and managing brain health. A new study finds that microbiota in the gut are essential for regulating microglia maturation and activation.

Publication types

Comment

MeSH terms

Animals
Central Nervous System / physiology*
Fatty Acids, Volatile / metabolism*
Female
Homeostasis / physiology*
Immunity, Innate / physiology*
Male
Microbiota / physiology*
Microglia / physiology*

Substances

Fatty Acids, Volatile

Grants and funding

R01 AG045034/AG/NIA NIH HHS/United States