Management of Noncardiac Comorbidities in Chronic Heart Failure

Cardiovasc Ther. 2015 Oct;33(5):300-15. doi: 10.1111/1755-5922.12141.

Abstract

Prevalence of heart failure is increasing, especially in the elderly population. Noncardiac comorbidities complicate heart failure care and are increasingly common in elderly patients with reduced or preserved ejection fraction heart failure, owing to prolongation of patient's lives by advances in chronic heart failure (CHF) management. Common comorbidities include respiratory disease, renal dysfunction, anemia, arthritis, obesity, diabetes mellitus, cognitive dysfunction, and depression. These conditions contribute to the progression of the disease and may alter the response to treatment, partly as polypharmacy is inevitable in these patients. Cardiologists and other physicians caring for patients with CHF need to be vigilant to comorbid conditions that complicate the care of these patients. There is now more guidance on management of noncardiac comorbidities in heart failure, and this article contains a comprehensive review of the most recent updates on management of noncardiac comorbidities in CHF.

Keywords: Comorbidities; Drug treatment; Heart failure; Management.

MeSH terms

  • Anemia / drug therapy
  • Anemia / epidemiology
  • Arthritis / drug therapy
  • Arthritis / epidemiology
  • Cognition Disorders / drug therapy
  • Cognition Disorders / epidemiology
  • Depression / drug therapy
  • Depression / epidemiology
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus / epidemiology
  • Disease Progression
  • Heart Failure / drug therapy*
  • Heart Failure / epidemiology*
  • Humans
  • Kidney Diseases / epidemiology
  • Kidney Diseases / therapy
  • Obesity / epidemiology
  • Obesity / therapy
  • Polypharmacy
  • Respiratory Tract Diseases / drug therapy
  • Respiratory Tract Diseases / epidemiology
  • Risk Factors