Cyclosporin A and psoriasis: a thermographic study

Acta Derm Venereol Suppl (Stockh). 1989:146:155-8.

Abstract

The thermographic method permits the making of a rigorous evaluation of the cutaneous blood flow by means of thermal recovery times after thermostimulation at 5 degrees C for 20 sec. The aim of the present study was to examine the blood flow of the psoriatic skin of 7 patients before and after a course of cyclosporin therapy, by means of this method. The results show a constant, initial hyperthermia with precocious thermal recovery times, in comparison with the healthy perilesional skin. Following therapy, a prolongation of the thermal recovery time was observed in all of the patients, together with a significant improvement of the dermatosis.

MeSH terms

  • Cyclosporins / therapeutic use*
  • Female
  • Humans
  • Male
  • Microcirculation
  • Middle Aged
  • Psoriasis / drug therapy*
  • Psoriasis / physiopathology
  • Regional Blood Flow / drug effects
  • Skin / blood supply*
  • Thermography / methods*

Substances

  • Cyclosporins