Heck-Mizoroki coupling of vinyliodide and applications in the synthesis of dienes and trienes

Chem Commun (Camb). 2015 Jul 21;51(57):11409-12. doi: 10.1039/c5cc03273c.

Abstract

Vinyliodide reacts chemoselectively under Heck-Mizoroki conditions with terminal alkenes, including vinylboronate esters, to give dienes. The resulting dienylboronates undergo Suzuki-Miyaura couplings with aryl, heteroaryl and alkenyl halides to access dienes and trienes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemical synthesis*
  • Alkenes / chemistry
  • Alkynes / chemical synthesis*
  • Alkynes / chemistry
  • Catalysis
  • Palladium / chemistry
  • Polyenes / chemical synthesis*
  • Polyenes / chemistry
  • Stereoisomerism
  • Vinyl Compounds / chemical synthesis
  • Vinyl Compounds / chemistry*

Substances

  • Alkenes
  • Alkynes
  • Polyenes
  • Vinyl Compounds
  • vinylboronate ester
  • Palladium