Bufavirus genotype 3 in Turkish children with severe diarrhoea

A Altay; T Yahiro; G Bozdayi; T Matsumoto; F Sahin; S Ozkan; A Nishizono; M Söderlund-Venermo; K Ahmed

doi:10.1016/j.cmi.2015.06.006

Bufavirus genotype 3 in Turkish children with severe diarrhoea

Clin Microbiol Infect. 2015 Oct;21(10):965.e1-4. doi: 10.1016/j.cmi.2015.06.006. Epub 2015 Jun 15.

Authors

A Altay¹, T Yahiro², G Bozdayi¹, T Matsumoto³, F Sahin⁴, S Ozkan⁵, A Nishizono³, M Söderlund-Venermo⁶, K Ahmed⁷

Affiliations

¹ Department of Medical Microbiology, Gazi University, Ankara, Turkey.
² Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia.
³ Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan.
⁴ Department of Paediatrics, Turkey.
⁵ Department of Public Health, Faculty of Medicine, Gazi University, Ankara, Turkey.
⁶ Department of Virology, Haartman Institute, University of Helsinki, Finland.
⁷ Department of Pathobiology and Medical Diagnostics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia; Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan; Research Promotion Institute, Oita University, Yufu, Japan. Electronic address: ahmed@oita-u.ac.jp.

PMID: 26086570
DOI: 10.1016/j.cmi.2015.06.006

Abstract

Recently a parvovirus called bufavirus (BuV) has been implicated as a causative agent of diarrhoea. To further reveal the epidemiology and genetic characteristics of BuV, this study was performed in Turkish children with diarrhoea. BuV was detected in 1.4% (8/583) of stool samples. All stool samples from healthy children (n = 148) were negative for BuV. Diarrhoea in BuV-positive patients was severe and occurred mainly during the colder months of the year. Complete genome sequences were generated from four BuVs. Only BuV3 was found, which was genetically and phylogenetically similar to Bhutanese BuV3, indicating that BuV3 is prevalent in Asian countries.

Keywords: Bufavirus; Turkey; children; diarrhoea; prevalence.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child, Preschool
Diarrhea / epidemiology*
Diarrhea / pathology*
Diarrhea / virology
Feces / virology
Female
Genome, Viral
Genotype*
Humans
Infant
Male
Parvoviridae Infections / epidemiology*
Parvoviridae Infections / pathology*
Parvoviridae Infections / virology
Parvovirus / classification*
Parvovirus / genetics
Parvovirus / isolation & purification*
Phylogeny
Prevalence
Seasons
Sequence Analysis, DNA
Sequence Homology
Turkey / epidemiology