Severe Pediatric Adenovirus 7 Disease in Singapore Linked to Recent Outbreaks across Asia

Emerg Infect Dis. 2015 Jul;21(7):1192-6. doi: 10.3201/eid2107.141443.

Abstract

During November 2012-July 2013, a marked increase of adenovirus type 7 (Ad7) infections associated with severe disease was documented among pediatric patients in Singapore. Phylogenetic analysis revealed close genetic links with severe Ad7 outbreaks in China, Taiwan, and other parts of Asia.

Keywords: Ad7; Asia; China; Human adenovirus; Malaysia; Singapore; death; invasive disease; mechanical ventilation; outbreak; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenovirus Infections, Human / epidemiology
  • Adenovirus Infections, Human / pathology*
  • Adenovirus Infections, Human / virology
  • Adenoviruses, Human / genetics*
  • Adolescent
  • Child
  • Child, Preschool
  • China / epidemiology
  • Disease Outbreaks*
  • Genes, Viral
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Phylogeny
  • Retrospective Studies
  • Singapore / epidemiology
  • Taiwan / epidemiology