We describe strategies for the construction of bacterial computing platforms by describing a number of results from the recently completed bacterial computing with engineered populations project. In general, the implementation of such systems requires a framework containing various components such as intracellular circuits, single cell input/output and cell-cell interfacing, as well as extensive analysis. In this overview paper, we describe our approach to each of these, and suggest possible areas for future research.
Keywords: conjugation; mathematical modelling; simulation; synthetic biology; unconventional computing.
© 2015 The Author(s) Published by the Royal Society. All rights reserved.