Endovascular Repair versus Open Repair for Isolated Descending Thoracic Aortic Aneurysm

Yonsei Med J. 2015 Jul;56(4):904-12. doi: 10.3349/ymj.2015.56.4.904.

Abstract

Purpose: To compare the outcomes of thoracic endovascular aortic repair (TEVAR) with those of open repair for descending thoracic aortic aneurysms (DTAA).

Materials and methods: We compared the outcomes of 114 patients with DTAA and proximal landing zones 3 or 4 after TEVAR to those of 53 patients after conventional open repairs. Thirty-day and late mortality were the primary endpoints, and early morbidities, aneurysm-related death, and re-intervention were the secondary endpoints.

Results: The TEVAR group was older and had more incidences of dissecting aneurysm. The mean follow-up was 36±26 months (follow-up rate, 97.8%). The 30-day mortality in the TEVAR and open repair groups were 3.5% and 9.4% (p=0.11). Perioperative stroke and paraplegia incidences were similar between the groups [5.3% vs. 7.5% (p=0.56) and 7.5% vs. 3.5% (p=0.26), respectively]. Respiratory failure occurred more in the open repair group (1.8% vs. 26.4%, p<0.01). The incidence of acute kidney injury requiring dialysis was higher in the open repair group (1.8% vs. 9.4%, p<0.01). The cumulative survival rate was higher in the TEVAR group at 2 to 5 years (79.6% vs. 58.3%, p=0.03). The free from re-intervention was lower in the TEVAR group (65.3% vs. 100%, p=0.02), and the free from aneurysm-related death in the TEVAR and open repair groups were 88.5% and 86.1% (p=0.45).

Conclusion: TEVAR is safe and effective for treating DTAAs with improved perioperative and long-term outcomes compared with open repair.

Keywords: Aortic aneurysm; aorta; cardiovascular surgical procedures; descending; endovascular procedures; outcome assessment.

MeSH terms

  • Age Factors
  • Aged
  • Aortic Aneurysm, Thoracic / mortality
  • Aortic Aneurysm, Thoracic / surgery*
  • Aortic Dissection / epidemiology*
  • Aortic Dissection / surgery
  • Aortic Rupture / mortality
  • Aortic Rupture / surgery*
  • Blood Vessel Prosthesis Implantation
  • Endovascular Procedures
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Republic of Korea
  • Stroke / etiology
  • Survival Rate
  • Time Factors
  • Treatment Outcome