Congenital Cytomegalovirus Infection in Monozygotic Twins with Twin-to-twin Transfusion Syndrome

Indian Pediatr. 2015 May;52(5):429-31. doi: 10.1007/s13312-015-0650-x.

Authors

Junya Nakajima¹, Daisuke Sunohara, Hisashi Kawashima

Affiliation

¹ Department of Pediatrics, Tokyo Medical University, Tokyo, Japan. Correspondence to: Dr Junya Nakajima, Department of Pediatrics, Tokyo Medical University, 6-7-1 Nishishinjuku Shinjuku-ku, Tokyo 160-0023, Japan. ob1.3po@hotmail.co.jp.

PMID: 26061933
DOI: 10.1007/s13312-015-0650-x

Abstract

Background: Symptoms of congenital cytomegalovirus infection remains unclear.

Case characteristics: Extremely low birth weight twins with twin-to-twin transfusion syndrome were infected with cytomegalovirus congenitally.

Observation: The donor showed neuronal impairment, whereas the recipient showed hepatic dysfunction.

Message: Intrauterine hemodynamics may be important in pathophysiology of congenital cytomegalovirus infection.

Publication types

Case Reports

MeSH terms

Adult
Brain / pathology
Cytomegalovirus Infections*
Female
Fetofetal Transfusion*
Humans
Infant
Infant, Newborn
Pregnancy
Pregnancy Complications, Infectious*
Treatment Outcome
Twins, Monozygotic*