Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases

Nadia Touisni; Nasreddine Kanfar; Sébastien Ulrich; Pascal Dumy; Claudiu T Supuran; Ahmad Mehdi; Jean-Yves Winum

doi:10.1002/chem.201501917

Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases

Chemistry. 2015 Jul 13;21(29):10249. doi: 10.1002/chem.201501917. Epub 2015 Jun 8.

Authors

Nadia Touisni¹, Nasreddine Kanfar¹, Sébastien Ulrich¹, Pascal Dumy¹, Claudiu T Supuran², Ahmad Mehdi³, Jean-Yves Winum⁴

Affiliations

¹ Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-ENSCM-Université de Montpellier, ENSCM, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex (France).
² Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence (Italy).
³ Institut Charles Gerhardt, UMR 5253, Equipe Chimie Moléculaire et Organisation du Solide, Université de Montpellier, Place Eugène Bataillon, 34095 Montpellier Cedex 05 (France).
⁴ Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-ENSCM-Université de Montpellier, ENSCM, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex (France). jean-yves.winum@univ-montp2.fr.

PMID: 26061872
DOI: 10.1002/chem.201501917

Abstract

Invited for the cover of this issue are Jean-Yves Winum and co-workers at University of Montpellier (France) and University of Florence (Italy). The image depicts the multivalency approach applied to zinc metalloenzyme carbonic anhydrases. Read the full text of the article at 10.1002/chem.201501037.