Propranolol in the Treatment of Infantile Hemangiomas: A Meta-Analysis in Chinese Patients

Pediatr Dermatol. 2015 Sep-Oct;32(5):e210-4. doi: 10.1111/pde.12627. Epub 2015 Jun 10.

Abstract

A meta-analysis was conducted to evaluate the efficacy of propranolol in the treatment of infantile hemangiomas (IHs) in Chinese infants. A statistically significant difference was found between infants treated using propranolol and those treated using corticosteroids (p < 0.001). The total effect pooled from 26 single-arm studies using meta-analysis of propranolol on IHs in Chinese infants was 93% (95% confidence interval 0.88, 0.96).

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Administration, Oral
  • Adrenal Cortex Hormones / administration & dosage*
  • Adrenal Cortex Hormones / adverse effects
  • Asian People / statistics & numerical data
  • Biopsy, Needle
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Follow-Up Studies
  • Hemangioma, Capillary / drug therapy*
  • Hemangioma, Capillary / ethnology
  • Hemangioma, Capillary / pathology*
  • Humans
  • Immunohistochemistry
  • Infant
  • Infant, Newborn
  • Propranolol / administration & dosage*
  • Propranolol / adverse effects
  • Randomized Controlled Trials as Topic
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / ethnology
  • Skin Neoplasms / pathology*
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Propranolol