Vitamin D and Sarcopenia/Falls

Joan M Lappe; Neil Binkley

doi:10.1016/j.jocd.2015.04.015

Vitamin D and Sarcopenia/Falls

J Clin Densitom. 2015 Oct-Dec;18(4):478-82. doi: 10.1016/j.jocd.2015.04.015. Epub 2015 Jun 6.

Authors

Joan M Lappe¹, Neil Binkley²

Affiliations

¹ Osteoporosis Research Center, Department of Medicine, Creighton University, Omaha, NE, USA. Electronic address: jmlappe@creighton.edu.
² Osteoporosis Clinical Research Program, Department of Medicine, University of Wisconsin, Madison, WI, USA.

PMID: 26059567
DOI: 10.1016/j.jocd.2015.04.015

Abstract

Maintenance of adequate vitamin D status is a stratagem to consider for sarcopenia prevention and treatment. Vitamin D deficiency is common and involves all ages of most racial/ethnic groups and both sexes. Evidence suggests that vitamin D is important for muscle strength and function, and prospective studies are underway to further define these effects. This article summarizes the potential effects of vitamin D on skeletal muscle structure and function and provides guidance for vitamin D supplementation in prevention and treatment of sarcopenia and falls.

Keywords: Falls; muscle function; sarcopenia; vitamin D.

MeSH terms

Accidental Falls / prevention & control*
Dietary Supplements
Female
Humans
Male
Sarcopenia / etiology
Sarcopenia / prevention & control*
Vitamin D / analogs & derivatives
Vitamin D / blood
Vitamin D / physiology
Vitamin D / therapeutic use*

Substances

Vitamin D
25-hydroxyvitamin D