Ménage a Trois to Form the Tricellular Junction

David Flores-Benitez; Elisabeth Knust

doi:10.1016/j.devcel.2015.05.020

Ménage a Trois to Form the Tricellular Junction

Dev Cell. 2015 Jun 8;33(5):501-3. doi: 10.1016/j.devcel.2015.05.020.

Authors

David Flores-Benitez¹, Elisabeth Knust²

Affiliations

¹ Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307-Dresden, Germany.
² Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307-Dresden, Germany. Electronic address: knust@mpi-cbg.de.

PMID: 26058055
DOI: 10.1016/j.devcel.2015.05.020

Abstract

Tricellular junctions tightly seal epithelia at the corners of three cells. In this issue of Developmental Cell, Byri et al. (2015) show that Anakonda, a novel Drosophila transmembrane protein, contains an unusual tripartite extracellular domain organization, which explains the tripartite septum filling the tricellular junction, previously revealed by ultrastructure analysis.

Publication types

Comment

MeSH terms

Animals
Animals, Genetically Modified / metabolism*
Drosophila Proteins / metabolism*
Drosophila melanogaster / metabolism*
Embryo, Nonmammalian / cytology*
Epithelium / growth & development*
Intercellular Junctions / physiology*
Tight Junctions / physiology*

Substances

Drosophila Proteins