[18F]Fluorodeoxyglucose PET/Computed Tomography in Gastrointestinal Malignancies

PET Clin. 2014 Oct;9(4):421-41, v-vi. doi: 10.1016/j.cpet.2014.07.001. Epub 2014 Aug 12.

Abstract

This article discusses the current state-of-the-art application of 2-deoxy-2-[(18)F]fluoro-d-glucose (FDG)-PET and FDG-PET/computed tomography (CT) in the management of patients with gastrointestinal malignancies. Gastrointestinal malignancies include many different cell types, several common malignancies of which may be imaged by FDG-PET/CT. This review focuses on gastric carcinoma, pancreatic carcinoma, hepatocellular carcinoma, cholangiocarcinoma, colorectal carcinoma, and stroma cell tumors. The role of FDG-PET/CT in staging these malignancies is discussed, in addition to (re)staging, detection of recurrent disease, patient selection/prognostication, and response assessment, using the currently available literature.

Keywords: GI; Gastrointestinal; Malignancy; PET/CT; [(18)F]Fluorodeoxyglucose.

Publication types

  • Review

MeSH terms

  • Colorectal Neoplasms / diagnostic imaging
  • Colorectal Neoplasms / pathology
  • Fluorodeoxyglucose F18*
  • Gastrointestinal Neoplasms / diagnostic imaging*
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / pathology
  • Liver Neoplasms / secondary
  • Multimodal Imaging*
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Staging
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / pathology
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Stomach Neoplasms / diagnostic imaging
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18