Abstract
A convenient method is presented that employs a DNA machine for protein biomarker detection. The detection limit is 400 times lower compared to the method without a DNA machine. This study provides a promising method that could realize most protein biomarker detections without the corresponding aptamers, using a DNA machine for signal amplification.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aptamers, Nucleotide / chemistry
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Aptamers, Nucleotide / metabolism
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Biomarkers / blood*
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Biosensing Techniques
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DNA / chemistry
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DNA / metabolism*
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Humans
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Nucleic Acid Amplification Techniques
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Prostate-Specific Antigen / blood
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Spectrometry, Fluorescence
Substances
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Aptamers, Nucleotide
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Biomarkers
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DNA
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Prostate-Specific Antigen