Catalytic C-H bond functionalisation of purine and pyrimidine nucleosides: a synthetic and mechanistic perspective

Chem Commun (Camb). 2015 Aug 4;51(60):11944-60. doi: 10.1039/c5cc03416g.

Abstract

C-H bond functionalisation of heteroarenes, especially nucleosides, has received a lot of attention in the past few years. This review describes the state-of the art in this area with a global aspiration for possibly functionalising purine and pyrimidine moieties in more complex biomolecular systems, such as DNA/RNA in the near future.'

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Carbon / chemistry
  • Catalysis
  • Chemistry Techniques, Synthetic / methods
  • DNA / chemical synthesis
  • DNA / chemistry
  • Purine Nucleosides / chemical synthesis
  • Purine Nucleosides / chemistry*
  • Pyrimidine Nucleosides / chemical synthesis
  • Pyrimidine Nucleosides / chemistry*
  • RNA / chemical synthesis
  • RNA / chemistry

Substances

  • Purine Nucleosides
  • Pyrimidine Nucleosides
  • RNA
  • Carbon
  • DNA