Feasibility study of high intensity focused ultrasound (HIFU) for the treatment of hydatid cysts of the liver

Ultrason Sonochem. 2015 Nov:27:712-716. doi: 10.1016/j.ultsonch.2015.05.025. Epub 2015 May 27.

Abstract

This study evaluates the feasibility of using high intensity focused ultrasound (HIFU) for the treatment of hydatid cysts of the liver. HIFU ablation was carried out in 62 patients with echinococcosis of the liver. The mean age of patients was 40.76±14.84 (range: 17-72 years). The effectiveness of the treatment was monitored in real-time by changes in the gray-scale, and by morphological studies, computed tomography, magnetic resonance imaging, and ultrasound. Criteria for evaluating the effectiveness of treatment in real time were outlines. Cytomorphological picture of destructive changes of parasitic elements was presented as well. Loss of embryonic elements of the parasite was observed at the subcellular level after HIFU-ablation and underlines the effectiveness of HIFU.

Keywords: HIFU; High intensity focused ultrasound; Hydatid cysts of the liver.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Echinococcosis / pathology
  • Echinococcosis / surgery*
  • Feasibility Studies
  • Female
  • High-Intensity Focused Ultrasound Ablation*
  • Humans
  • Liver Diseases, Parasitic / pathology
  • Liver Diseases, Parasitic / surgery*
  • Middle Aged
  • Young Adult