Sameness: The regulatory crux with nanomaterial identity and grouping schemes for hazard assessment

Tobias Walser; Christoph Studer

doi:10.1016/j.yrtph.2015.05.031

Sameness: The regulatory crux with nanomaterial identity and grouping schemes for hazard assessment

Regul Toxicol Pharmacol. 2015 Aug;72(3):569-71. doi: 10.1016/j.yrtph.2015.05.031. Epub 2015 Jun 3.

Authors

Tobias Walser¹, Christoph Studer¹

Affiliation

¹ Federal Office of Public Health, 3003 Bern, Switzerland.

PMID: 26049104
DOI: 10.1016/j.yrtph.2015.05.031

Abstract

Regulators and industry need clear rules for identification and grouping of nanomaterials for a streamlined quantitative hazard evaluation. Therefore, we provide convincing reasons for (i) why to introduce pragmatic definition of identities for nanomaterials, (ii) how to combine them into entities, and ultimately (iii) how the entities might be evaluated with testing strategies based on clouds of similar nanomaterials.

Keywords: Entity of nanomaterials; Grouping; Hazard assessment of nanomaterials; Identity of nanomaterials; Regulatory toxicology; Sameness; Testing strategy.

MeSH terms

Humans
Nanostructures / classification*
Nanostructures / toxicity*
Risk Assessment
Toxicity Tests