Draft Genome Sequence of Mycobacterium tuberculosis Strain MT11, Which Represents a New Lineage

Djaltou Aboubaker Osman; Michael Phelippeau; Didier Musso; Catherine Robert; Caroline Michelle; Olivier Croce; Michel Drancourt

doi:10.1128/genomeA.00573-15

Draft Genome Sequence of Mycobacterium tuberculosis Strain MT11, Which Represents a New Lineage

Genome Announc. 2015 Jun 4;3(3):e00573-15. doi: 10.1128/genomeA.00573-15.

Authors

Djaltou Aboubaker Osman, Michael Phelippeau¹, Didier Musso², Catherine Robert¹, Caroline Michelle¹, Olivier Croce¹, Michel Drancourt³

Affiliations

¹ Aix Marseille Université, URMITE, UMR CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
² Institut Louis Malardé, Papeete, French Polynesia.
³ Aix Marseille Université, URMITE, UMR CNRS 7278, IRD 198, INSERM 1095, Marseille, France michel.drancourt@univ-amu.fr.

Abstract

We sequenced the genome of Mycobacterium tuberculosis strain MT11, which exhibits a specific 16S rRNA gene mutation found in 6% of French Polynesian M. tuberculosis isolates. It comprises a 4,110,293-bp chromosome with 65.15% G+C content, and it encodes 3,949 proteins and contains 85 predicted RNA genes. The TbD1 region is absent in strain MT11 as in modern M. tuberculosis strains.