Antibacterial and antifungal compounds from marine fungi

Mar Drugs. 2015 Jun 2;13(6):3479-513. doi: 10.3390/md13063479.

Abstract

This paper reviews 116 new compounds with antifungal or antibacterial activities as well as 169 other known antimicrobial compounds, with a specific focus on January 2010 through March 2015. Furthermore, the phylogeny of the fungi producing these antibacterial or antifungal compounds was analyzed. The new methods used to isolate marine fungi that possess antibacterial or antifungal activities as well as the relationship between structure and activity are shown in this review.

Keywords: Aspergillus; antibacterial; antibiotic; antifungal; antimicrobial; marine fungus; metabolites; polyketide.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Aquatic Organisms / microbiology
  • Fungi / isolation & purification
  • Fungi / metabolism*
  • Phylogeny
  • Structure-Activity Relationship

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents