Optimized core-shell Au@Ag nanoparticles for label-free Raman determination of trace Rhodamine B with cancer risk in food product

Hui Wang; Xiaoyu Guo; Shuyue Fu; Tianxi Yang; Ying Wen; Haifeng Yang

doi:10.1016/j.foodchem.2015.04.122

Optimized core-shell Au@Ag nanoparticles for label-free Raman determination of trace Rhodamine B with cancer risk in food product

Food Chem. 2015 Dec 1:188:137-42. doi: 10.1016/j.foodchem.2015.04.122. Epub 2015 Apr 30.

Authors

Hui Wang¹, Xiaoyu Guo², Shuyue Fu¹, Tianxi Yang¹, Ying Wen¹, Haifeng Yang³

Affiliations

¹ The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, PR China.
² The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, PR China. Electronic address: gxy2012@shnu.edu.cn.
³ The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, PR China. Electronic address: haifengyang@yahoo.com.

PMID: 26041175
DOI: 10.1016/j.foodchem.2015.04.122

Abstract

A simple and reliable method based on surface-enhanced Raman scattering (SERS) with a portable Raman system is described for sensitive determination of trace levels of Rhodamine B (RB) in hot sauce samples. The sodium salt of phytic acid (IP6) stabilized Au@Ag core-shell bimetallic nanoparticles are constructed and used as SERS substrate, yielding high Raman enhancement of RB. The limit of detection for RB in water is 5 nM (2 ppb), which is below China Exit and Entry Inspection and Quarantine Bureau's tolerance level of 5 ppb. Also, the proposed easy assay of IP6-Au@Ag NPs combining with portable Raman system could be applied for on-site monitoring RB in hot sauce.

Keywords: Ag–Au bimetal; Core–shell nanostructure; Raman probe; Rhodamine B.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gold / chemistry*
Metal Nanoparticles / chemistry*
Neoplasms / chemistry
Neoplasms / etiology*
Rhodamines / chemistry*
Risk Factors
Silver / chemistry*
Spectrum Analysis, Raman / methods

Substances

Rhodamines
Silver
Gold
rhodamine B