Benzodiazepine prescribing guideline adherence and misuse potential in Irish minors

Int J Clin Pharm. 2015 Oct;37(5):749-52. doi: 10.1007/s11096-015-0138-8. Epub 2015 Jun 4.

Abstract

Background: The Good Prescribing Practice for Clinicians guidelines were published in 2002 in Ireland to guide General Practitioners about prescribing benzodiazepines. There has been no research to-date to measure compliance by General Practitioners. Inappropriate prescribing to minors may result in increased use or misuse of benzodiazepines.

Objective: The purpose of this study was to evaluate the prescribing of benzodiazepines to minors in Ireland against the Good Prescribing Practice for Clinicians guidelines.

Method: Data for medicines dispensed between January 2009 and December 2012 from the Health Intelligence Ireland database were accessed and analysed. This database contains information about government-subsidised community-pharmacy-dispensed medicines.

Results: Benzodiazepine prescribing to minors increased by 10.2% between 2009 and 2012. Almost 15% of patients (n = 2193) were prescribed benzodiazepines for greater than four weeks; which contravenes the guidelines. Approximately half (51.4%) of prescribers who contravened this guideline, prescribed all their benzodiazepines in quantities of greater than one week, against the recommendations of the guidelines.

Conclusion: The consequences of prescribing against National Guidelines can result in patients who become long-term benzodiazepine users and thus place an increased burden upon the healthcare system. The reasons for non-compliance by GPs should be investigated to find solutions.

Keywords: Adolescents; Benzodiazepines; Children; Drug utilisation; Ireland.

MeSH terms

  • Adolescent
  • Benzodiazepines / therapeutic use*
  • Child
  • Databases, Pharmaceutical
  • Drug Utilization / trends*
  • Guideline Adherence / statistics & numerical data*
  • Humans
  • Inappropriate Prescribing / statistics & numerical data*
  • Ireland
  • Minors / statistics & numerical data*
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Time Factors

Substances

  • Benzodiazepines