High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping

ACS Appl Mater Interfaces. 2015 Jun 17;7(23):12635-8. doi: 10.1021/acsami.5b03969. Epub 2015 Jun 8.

Abstract

We describe the preparation of rapid prototyped parallelized microfluidic drop-maker devices. The manufacturing technique facilitates stacking of the drop-makers vertically on top of each other allowing for a reduced footprint and minimized dead-volume through efficient design of the distribution channels. We showcase the potential of the additive manufacturing technique for microfluidics and the performance of the parallelized device by producing large amounts of microgels with a diameter of ca. 500 μm, a size that is inaccessible using traditional synthetic approaches.

Keywords: 3D printing; additive manufacturing; microfluidics; microgel; parallelization; rapid prototyping; upscaling.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't