Graphene-Based Materials in Regenerative Medicine

Adv Healthc Mater. 2015 Jul 15;4(10):1451-68. doi: 10.1002/adhm.201500203. Epub 2015 Jun 2.

Abstract

Graphene possesses many unique properties such as two-dimensional planar structure, super conductivity, chemical and mechanical stability, large surface area, and good biocompatibility. In the past few years, graphene-based materials have risen as a shining star on the path of researchers seeking new materials for future regenerative medicine. Herein, the recent research advances made in graphene-based materials mostly utilizing the mechanical and electrical properties of graphene are described. The most exciting findings addressing the impact of graphene-based materials on regenerative medicine are highlighted, with particular emphasis on their applications including nerve, bone, cartilage, skeletal muscle, cardiac, skin, adipose tissue regeneration, and their effects on the induced pluripotent stem cells. Future perspectives and emerging challenges are also addressed in this Review article.

Keywords: graphene; regenerative medicine; stem cells; tissue engineering.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bone Regeneration
  • Cell Differentiation
  • Graphite / chemistry*
  • Graphite / toxicity
  • Humans
  • Muscle, Skeletal / physiology
  • Neurons / physiology
  • Regeneration
  • Regenerative Medicine*
  • Stem Cells / cytology
  • Stem Cells / metabolism
  • Tissue Engineering

Substances

  • Graphite