Gastrointestinal stromal tumour in a recipient with kidney transplantation

BMJ Case Rep. 2015 Jun 1:2015:bcr2014207178. doi: 10.1136/bcr-2014-207178.

Abstract

Immunosuppression is associated with an increased risk of post-transplant malignancies. Gastrointestinal stromal tumours are the most common mesenchymal tumours of the gastrointestinal tract. However, they have seldom been reported recipient with transplantation. In this report, a 46-year-old woman, a recipient with kidney transplantation, who developed a gastric tumour is presented. Removal of this tumour required a partial gastrectomy. Histopathology and immunohistochemistry examinations revealed a high-risk gastric stromal tumour. Adjuvant imatinib mesylate treatment was initiated. There was no evidence of tumour recurrence at 12-month follow-up.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / administration & dosage*
  • Chemotherapy, Adjuvant
  • Female
  • Gastrectomy / methods*
  • Gastrointestinal Stromal Tumors / diagnosis*
  • Gastrointestinal Stromal Tumors / drug therapy
  • Gastrointestinal Stromal Tumors / surgery
  • Humans
  • Imatinib Mesylate / administration & dosage*
  • Kidney Transplantation / adverse effects*
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / drug therapy
  • Stomach Neoplasms / surgery
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Imatinib Mesylate