Infectious causes of fever of unknown origin

Clin Med (Lond). 2015 Jun;15(3):285-7. doi: 10.7861/clinmedicine.15-3-285.

Abstract

The causes of fever of unknown origin (FUO) are changing because advances in clinical practice and diagnostics have facilitated the identification of some infections. A variety of bacterial infections can cause FUO, and these can be divided into those that are easy to identify using culture and those that require serological or molecular tests for identification. A number of viral, parasitic and fungal infections can also cause prolonged fever. This article summarises the clinical features and diagnostic strategy of these infections.

Keywords: Fever; chronic; origin; pyrexia; unknown.

MeSH terms

  • Bacterial Infections / microbiology
  • Diagnosis, Differential
  • Fever of Unknown Origin / microbiology*
  • Fever of Unknown Origin / parasitology*
  • Fever of Unknown Origin / virology
  • Humans
  • Infectious Mononucleosis / virology
  • Mycoses / microbiology
  • Parasitic Diseases / parasitology