Drug-eluting balloons to treat iliac in-stent restenosis

Ann Vasc Surg. 2015 Aug;29(6):1315.e3-6. doi: 10.1016/j.avsg.2015.02.021. Epub 2015 May 29.

Abstract

Background: To report our experience in the use of drug-eluting balloons (DEBs) for the treatment of symptomatic iliac in-stent restenosis (ISR).

Case reports: Six patients underwent treatment using DEBs for iliac ISRs in our centers between September 2011 and May 2014. The patients were predominantly women (4 of 6, 66.7%) with a mean age of 67.2 years (range, 46-75 years). Technical success was achieved in all cases. During the follow-up (mean duration, 15.5 months; range, 3-30 months), healing of the lesions/relief of symptoms was obtained in 5 of 6 cases (83.3%). Estimated 2-year rates of overall patency and limb salvage were 100%.

Conclusions: The use of DEBs in the treatment of iliac ISR is safe and effective. The early and 2-year outcomes are promising. However, further experience with larger patient groups is needed.

MeSH terms

  • Aged
  • Angioplasty, Balloon / adverse effects*
  • Angioplasty, Balloon / instrumentation*
  • Coated Materials, Biocompatible*
  • Constriction, Pathologic
  • Female
  • Humans
  • Iliac Artery* / physiopathology
  • Limb Salvage
  • Male
  • Middle Aged
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / physiopathology
  • Peripheral Arterial Disease / therapy*
  • Recurrence
  • Retreatment
  • Stents*
  • Time Factors
  • Treatment Outcome
  • Vascular Access Devices*
  • Vascular Patency

Substances

  • Coated Materials, Biocompatible