Abstract
Diabetes is a multifactorial disease, with multiple pathophysiologic abnormalities. This means that a combination of drugs, acting upon as many pathologic mechanisms as possible, is necessary for optimal management of the syndrome. This article discusses how a rational combination of oral anti-diabetic drugs can be chosen and used in primary care practice.
Keywords:
Metformin, Sulfonylureas, Pioglitazone, Alpha glucosidase inhibitors, DPP4 inhibitors, Oral anti-diabetic drugs..
MeSH terms
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Canagliflozin / therapeutic use
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Diabetes Mellitus, Type 2 / drug therapy*
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Dipeptidyl-Peptidase IV Inhibitors / therapeutic use*
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Drug Combinations
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Drug Therapy, Combination
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Glycoside Hydrolase Inhibitors / therapeutic use*
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Humans
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Hypoglycemic Agents / therapeutic use*
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Metformin / therapeutic use
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Pioglitazone
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Primary Health Care*
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Sodium-Glucose Transporter 2 Inhibitors*
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Sulfonylurea Compounds / therapeutic use*
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Thiazolidinediones / therapeutic use
Substances
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Dipeptidyl-Peptidase IV Inhibitors
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Drug Combinations
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Glycoside Hydrolase Inhibitors
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Hypoglycemic Agents
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Sodium-Glucose Transporter 2 Inhibitors
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Sulfonylurea Compounds
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Thiazolidinediones
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Canagliflozin
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Metformin
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Pioglitazone