Imported Lassa fever: a report of 2 cases in Ghana

BMC Infect Dis. 2015 May 29:15:217. doi: 10.1186/s12879-015-0956-2.

Abstract

Background: Lassa fever is a potentially fatal acute viral illness caused by Lassa virus which is carried by rodents and is endemic in some West African countries. Importation of emerging infections such as Lassa fever, Ebola Virus Disease and other viral hemorrhagic fevers into non endemic regions is a growing threat particularly as international travel and commitments in resolving conflicts in endemic countries in the West Africa sub-region continue.

Case presentation: We report the first two recorded imported cases of Lassa fever among Ghanaian Peace keepers in rural Liberia, who became ill while on Peace keeping mission. They were subsequently evacuated to the UN level IV hospital in Accra, where their illnesses were laboratory confirmed. One of the patients recovered with ribavirin treatment and supportive therapy. No secondary clinical cases occurred in Ghana.

Conclusions: Healthcare providers at all levels of care should thus have a high index of suspicion for these infectious diseases and adopt standard infection control measures when treating patients in endemic regions or returning travelers from an endemic region with a febrile illness even of a known etiology.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use*
  • Communicable Diseases, Emerging
  • Contact Tracing*
  • Ghana
  • Humans
  • Lassa Fever / diagnosis
  • Lassa Fever / drug therapy*
  • Lassa Fever / transmission
  • Lassa virus / genetics
  • Liberia
  • Male
  • Military Personnel*
  • Public Health
  • Ribavirin / therapeutic use*
  • Travel*

Substances

  • Antiviral Agents
  • Ribavirin