Genome Anatomy of Streptococcus parasanguinis Strain C1A, Isolated from a Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Reveals Unusual Genomic Features

Kok-Gan Chan; Kim Tien Ng; Yong Kek Pang; Teik Min Chong; Adeeba Kamarulzaman; Wai-Fong Yin; Kok Keng Tee

doi:10.1128/genomeA.00541-15

Genome Anatomy of Streptococcus parasanguinis Strain C1A, Isolated from a Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Reveals Unusual Genomic Features

Genome Announc. 2015 May 28;3(3):e00541-15. doi: 10.1128/genomeA.00541-15.

Authors

Kok-Gan Chan¹, Kim Tien Ng², Yong Kek Pang², Teik Min Chong³, Adeeba Kamarulzaman², Wai-Fong Yin³, Kok Keng Tee²

Affiliations

¹ Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia kokgan@um.edu.my.
² Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
³ Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.

Abstract

Streptococcus parasanguinis causes invasive diseases. However, the mechanism by which it causes disease remains unclear. Here, we describe the complete genome sequence of S. parasanguinis C1A, isolated from a patient diagnosed with an acute exacerbation of chronic obstructive pulmonary disease. Several genes that might be associated with pathogenesis are also described.