Vitiligo: successful combination treatment based on oral low dose cytokines and different topical treatments

T Lotti; J Hercogova; U Wollina; A A Chokoeva; Z Zarrab; S Gianfaldoni; M G Roccia; M Fioranelli; G Tchernev

Vitiligo: successful combination treatment based on oral low dose cytokines and different topical treatments

J Biol Regul Homeost Agents. 2015 Jan-Mar;29(1 Suppl):53-8.

Authors

T Lotti¹, J Hercogova², U Wollina³, A A Chokoeva⁴, Z Zarrab⁵, S Gianfaldoni⁶, M G Roccia⁷, M Fioranelli⁸, G Tchernev⁴

Affiliations

¹ Professor and Chair of Dermatology, University of Rome G. Marconi Rome, Italy.
² Dept. Dermatology, 2nd Medical School, Charles University, Prague, Czech Republic.
³ Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
⁴ Onkoderma-Policlinic for Dermatology, Venereology and Dermatologic surgery, Sofia, Bulgaria.
⁵ University of Rome G. Marconi, Rome, Italy.
⁶ Department of dermatologic Sciences, University of Florence, Florence, Italy.
⁷ Chandigarh University, Punjab, India.
⁸ Associate Professor of Physiology, University B.I.S. Group of Institutions, Punjab Technical University, Punjab, India.

PMID: 26016984

Abstract

The current treatments for Vitiligo are not completely satisfactory in terms of clinical, aesthetic and compliance results for patients. Recently, combination therapies had been introduced with positive results. In this paper the combination between systemic oral treatment with Low Dose Cytokines in association with other topical treatments was evaluated. Positive results were obtained both with Low Dose Cytokines alone or in association with microphototherapy with positive percentage of skin repigmentation varying between 74% and 90%. Collected data allow the authors to affirm that the treatment with oral low dose SKA drugs is efficacious per se and highly efficacious in association with targeted phototherapy.