Metal nanoparticles: a theranostic nanotool against cancer

Drug Discov Today. 2015 Sep;20(9):1143-51. doi: 10.1016/j.drudis.2015.05.009. Epub 2015 May 22.

Abstract

Cancer remains one of the most deadly diseases worldwide, but conventional anticancer therapies come with several drawbacks. Therefore, there is a need to develop new anticancer strategies. Theranostics is a strategy that combines treatment with diagnosis and monitoring. Metal nanoparticles are proposed as one of the most promising theranostic agents for the treatment of cancer. Thus, metals including iron, gold (Au), silver (Ag), zinc (Zn), and titanium, have potential as anticancer agents, either inherently or as a result of surface modifications. As a functional component of theranostic tools, metal nanoparticles have crucial dual roles as a diagnostic and active therapeutic agent for the treatment of cancer.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / therapeutic use
  • Drug Design
  • Humans
  • Metal Nanoparticles / administration & dosage*
  • Neoplasms / diagnosis
  • Neoplasms / drug therapy*
  • Neoplasms / pathology
  • Theranostic Nanomedicine / methods

Substances

  • Antineoplastic Agents