Electrochromic polyoxometalate material as a sensor of bacterial activity

Chem Commun (Camb). 2015 Jun 25;51(50):10119-22. doi: 10.1039/c5cc03301b. Epub 2015 May 26.

Abstract

Lactobacillus fermentum, a bacterium of human microbiota, acts as an electron donor for the electrochromic [P2Mo(VI)18O62](6-). Since the reductive capacity of L. fermentum correlates with its metabolic activity, the reaction with [P2Mo(VI)18O62](6-) affords a means of evaluating its activity. Following this logic, we have concluded that vancomycin severely affects the activity of L. fermentum whereas omeprazole does not.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electron Transport / drug effects
  • Limosilactobacillus fermentum / drug effects
  • Limosilactobacillus fermentum / metabolism*
  • Omeprazole / pharmacology
  • Tungsten Compounds / metabolism*
  • Vancomycin / pharmacology

Substances

  • Tungsten Compounds
  • polyoxometalate I
  • Vancomycin
  • Omeprazole