Mechanical and hyperthermic properties of magnetic nanocomposites for biomedical applications

Kwabena Kan-Dapaah; Nima Rahbar; Abdullahi Tahlil; David Crosson; Nan Yao; Wole Soboyejo

doi:10.1016/j.jmbbm.2015.04.023

Mechanical and hyperthermic properties of magnetic nanocomposites for biomedical applications

J Mech Behav Biomed Mater. 2015 Sep:49:118-28. doi: 10.1016/j.jmbbm.2015.04.023. Epub 2015 Apr 30.

Authors

Kwabena Kan-Dapaah¹, Nima Rahbar², Abdullahi Tahlil², David Crosson², Nan Yao³, Wole Soboyejo⁴

Affiliations

¹ Department of Materials Science and Engineering, African University of Science and Technology, Federal Capital Territory, Abuja, Nigeria; Department of Biomedical Engineering, University of Ghana, Legon, Accra, Ghana; Department of Civil and Environmental Engineering, Worcester Polytechnic Institute, Worcester, MA 01609, USA.
² Department of Civil and Environmental Engineering, Worcester Polytechnic Institute, Worcester, MA 01609, USA.
³ Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, 08544, USA.
⁴ Department of Materials Science and Engineering, African University of Science and Technology, Federal Capital Territory, Abuja, Nigeria; Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, 08544, USA; Princeton Institute for Science and Technology of Materials, Princeton University, Princeton, NJ, 08544, USA. Electronic address: soboyejo@princeton.edu.

PMID: 26005843
DOI: 10.1016/j.jmbbm.2015.04.023

Abstract

An understanding of the properties of multifunctional materials is important for the design of devices for biomedical applications. In this paper, a combination of experiments and models was used to study the mechanical and hyperthermic properties of magnetic nanoparticles (MNP)-filled PDMS composites for biomedical applications. These are studied as a function of the weight of MNP, γ-Fe2O3. The results showed the effects on mechanical behavior, and specific losses in a magnetic field. The measured Young's moduli are in good agreement with the moduli predicted from the Bergström-Boybce model. Specific losses calculated from magnetic measurements are used to predict the thermal dose under in-vivo conditions. The implications of the results were discussed for potential applications in biomedical devices.

Keywords: Biomedical devices; Magnetic nanocomposites; Magnetic nanoparticles; Polydimethylsiloxane.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biocompatible Materials / chemistry*
Compressive Strength
Dimethylpolysiloxanes / chemistry
Elastic Modulus
Ferric Compounds / chemistry*
Materials Testing*
Mechanical Phenomena*
Models, Theoretical
Nanocomposites / chemistry*
Nanoparticles / chemistry*
Temperature*
Tensile Strength

Substances

Biocompatible Materials
Dimethylpolysiloxanes
Ferric Compounds
ferric oxide
baysilon