Arrhythmias in dilated cardiomyopathy

Saurabh Kumar; William G Stevenson; Roy M John

doi:10.1016/j.ccep.2015.03.005

Arrhythmias in dilated cardiomyopathy

Card Electrophysiol Clin. 2015 Jun;7(2):221-33. doi: 10.1016/j.ccep.2015.03.005. Epub 2015 Apr 1.

Authors

Saurabh Kumar¹, William G Stevenson¹, Roy M John²

Affiliations

¹ Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
² Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: Rjohn2@partners.org.

PMID: 26002388
DOI: 10.1016/j.ccep.2015.03.005

Abstract

Patients with dilated cardiomyopathies (DCM) face a significant burden of arrhythmias, including conduction defects such as atrioventricular block and interventricular delay in the form of left bundle branch block, resulting in altered electromechanical coupling that can exacerbate heart failure. Atrial fibrillation is common and carries an adverse prognosis. Ventricular arrhythmias and sudden cardiac death generally occur late in the disease course. Sustained monomorphic ventricular tachycardia accounts for most of the sustained ventricular arrhythmias in DCM. This article summarizes common forms of arrhythmias encountered in patients with DCM, and reviews the relevant electrophysiologic basis of these arrhythmias and their management.

Keywords: Atrial fibrillation; Atrial flutter; Atrioventricular block; Catheter ablation; Dilated cardiomyopathy; Lamin A/C cardiomyopathy; Ventricular tachycardia.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Arrhythmias, Cardiac*
Cardiomyopathy, Dilated*
Catheter Ablation
Humans