Bouncing off the Walls: Excited Protein Complexes Tell Their Story

Albert Konijnenberg; Frank Sobott

doi:10.1016/j.chembiol.2015.05.004

Bouncing off the Walls: Excited Protein Complexes Tell Their Story

Chem Biol. 2015 May 21;22(5):563-4. doi: 10.1016/j.chembiol.2015.05.004.

Authors

Albert Konijnenberg¹, Frank Sobott²

Affiliations

¹ Biomolecular & Analytical Mass Spectrometry Group, Department of Chemistry, University of Antwerp, 2020 Antwerp, Belgium.
² Biomolecular & Analytical Mass Spectrometry Group, Department of Chemistry, University of Antwerp, 2020 Antwerp, Belgium; UA-VITO Centre for Proteomics, University of Antwerp, 2020 Antwerp, Belgium. Electronic address: frank.sobott@uantwerpen.be.

PMID: 26000743
DOI: 10.1016/j.chembiol.2015.05.004

Abstract

"Native" mass spectrometry has become a valuable tool for structural biology. In this issue of Chemistry & Biology, Quintyn et al. (2015) show that modified instruments capable of surface-induced dissociation allow dissection of protein complexes in a way that is reminiscent of their native topology and architecture.

Publication types

Comment

MeSH terms

Ligands*
Proteins / chemistry*

Substances

Ligands
Proteins