Managing aortic aneurysms and dissections during pregnancy

Expert Rev Cardiovasc Ther. 2015 Jun;13(6):703-14. doi: 10.1586/14779072.2015.1042862. Epub 2015 May 17.

Abstract

Cardiovascular diseases during pregnancy account for significant morbidity and mortality, with aortic aneurysms, complicated by aortic dissection or rupture, being high on the list of underlying causes in this category. Correct knowledge of the diagnosis, risks and treatment is mandatory to improve the outcome and save lives. In this article, the authors aim to provide an overview of the underlying causes and risk factors for aortic aneurysms and dissections during pregnancy, while presenting the ways of preventing and treating these conditions. Although an important focus lies on the proximal part of the aorta due to it bearing the greatest risk for complications and being more frequently implicated in aortic disease in younger subjects, many aspects on the etiology and underlying diseases also apply to the other parts of the vessel.

Keywords: Marfan syndrome; Turner syndrome; beta-blockers; bicuspid aortic valve; coarctation; pregnancy; thoracic aneurysm; thoracic dissection; valve-sparing surgery.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Aortic Aneurysm / complications
  • Aortic Aneurysm / diagnosis
  • Aortic Aneurysm / therapy*
  • Aortic Dissection / complications
  • Aortic Dissection / diagnosis
  • Aortic Dissection / therapy*
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / diagnosis
  • Pregnancy Complications, Cardiovascular / physiopathology
  • Pregnancy Complications, Cardiovascular / therapy*
  • Risk Factors