[Portal vein thrombosis with sepsis caused by inflammation at colonic stent insertion site]

Korean J Gastroenterol. 2015 May;65(5):316-20. doi: 10.4166/kjg.2015.65.5.316.
[Article in Korean]

Abstract

Portal vein thrombosis is an uncommon but an important cause of portal hypertension. The most common etiological factors of portal vein thrombosis are liver cirrhosis and malignancy. Albeit rare, portal vein thrombosis can also occur in the presence of local infection and inflammation such as pancreatitis or cholecystitis. A 52-year-old male was admitted because of general weakness and poor oral intake. He had an operation for colon cancer 18 months ago. However, colonic stent had to be inserted afterwards because stricture developed at anastomosis site. Computed tomography taken at admission revealed portal vein thrombosis and inflammation at colonic stent insertion site. Blood culture was positive for Escherichia coli. After antibiotic therapy, portal vein thrombosis resolved. Herein, we report a case of portal vein thrombosis with sepsis caused by inflammation at colonic stent insertion site which was successfully treated with antibiotics.

Keywords: Anti-bacterial agents; Inflammation; Portal vein thrombosis; Sepsis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cholecystitis / etiology
  • Colonic Neoplasms / pathology
  • Colonic Neoplasms / therapy
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / etiology
  • Humans
  • Inflammation / etiology*
  • Liver / diagnostic imaging
  • Male
  • Middle Aged
  • Pancreatitis / etiology
  • Portal Vein
  • Sepsis / diagnosis*
  • Sepsis / drug therapy
  • Sepsis / microbiology
  • Sigmoidoscopy
  • Stents / adverse effects*
  • Tomography, X-Ray Computed
  • Venous Thrombosis / complications
  • Venous Thrombosis / diagnosis*

Substances

  • Anti-Bacterial Agents