Heck-Suzuki Tandem Reaction for the Synthesis of 3-Benzazepines

Anatoly A Peshkov; Vsevolod A Peshkov; Olga P Pereshivko; Kristof Van Hecke; Rakesh Kumar; Erik V Van der Eycken

doi:10.1021/acs.joc.5b00670

Heck-Suzuki Tandem Reaction for the Synthesis of 3-Benzazepines

J Org Chem. 2015 Jul 2;80(13):6598-608. doi: 10.1021/acs.joc.5b00670. Epub 2015 Jun 12.

Authors

Anatoly A Peshkov, Vsevolod A Peshkov, Olga P Pereshivko, Kristof Van Hecke¹, Rakesh Kumar, Erik V Van der Eycken

Affiliation

¹ ‡Department of Inorganic and Physical Chemistry, Gent University, Krijgslaan 281 S3, B-9000 Gent, Belgium.

PMID: 25996648
DOI: 10.1021/acs.joc.5b00670

Abstract

A novel procedure for the Heck-Suzuki tandem reaction suitable for the construction of nitrogen-containing medium rings was developed to provide access toward the 3-benzazepine framework.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzazepines / chemical synthesis*
Benzazepines / chemistry
Catalysis
Molecular Structure
Nitrogen / chemistry*

Substances

Benzazepines
Nitrogen