Recent developments in atmospheric pressure photoionization-mass spectrometry

Tiina J Kauppila; Jack A Syage; Thorsten Benter

doi:10.1002/mas.21477

Recent developments in atmospheric pressure photoionization-mass spectrometry

Mass Spectrom Rev. 2017 May;36(3):423-449. doi: 10.1002/mas.21477. Epub 2015 May 18.

Authors

Tiina J Kauppila¹, Jack A Syage², Thorsten Benter³

Affiliations

¹ Faculty of Pharmacy, University of Helsinki, P.O. Box 56, 00014, Finland.
² Morpho Detection, 1251 E. Dyer Rd., Santa Ana, CA 92705, USA.
³ Department of Physical and Theoretical Chemistry, University of Wuppertal, Gaußstr. 20, 42119 Wuppertal, Germany.

PMID: 25988849
DOI: 10.1002/mas.21477

Abstract

Recent developments in atmospheric pressure photoionization (APPI), which is one of the three most important ionization techniques in liquid chromatography-mass spectrometry, are reviewed. The emphasis is on the practical aspects of APPI analysis, its combination with different separation techniques, novel instrumental developments - especially in gas chromatography and ambient mass spectrometry - and the applications that have appeared in 2009-2014. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 36:423-449, 2017.

Keywords: ambient mass spectrometry; atmospheric pressure photoionization; dopant; gas chromatography-mass spectrometry; liquid chromatography-mass spectrometry.

Publication types

Review
Research Support, Non-U.S. Gov't