Chemical composition, antioxidant and antibacterial properties of Pteranthus dichotomus from Algerian Sahara

Nat Prod Res. 2016;30(6):700-4. doi: 10.1080/14786419.2015.1038811. Epub 2015 May 15.

Abstract

The phytochemical study of ethyl acetate and n-butanol extracts of Pteranthus dichotomus Forssk. led to the isolation and identification of 11 compounds, including three glycolipids 1-3, one lignan 4, three flavonoids 5-7 and four phytosterols 8-11. Structures of the isolated compounds have been elucidated by analysis of 1D and 2D NMR data, and mass spectrometry EI-MS and ESI-MS and by comparison with literature data. Furthermore, the ethyl acetate and n-butanol extracts were examined for their antioxidant and antibacterial activities. The results showed that both extracts (PDAC and PDBU) had a moderate antioxidant activity (IC50 = 375.514 μg/mL and 691.333 μg/mL) respectively.

Keywords: Caryophyllaceae; ESI; NMR; Pteranthus dichotomus; antibacterial activity; antioxidant activity; flavonoids; glycolipids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa, Northern
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Caryophyllaceae / chemistry*
  • Flavonoids / chemistry*
  • Flavonoids / isolation & purification
  • Inhibitory Concentration 50
  • Molecular Structure
  • Phytochemicals / chemistry
  • Phytochemicals / isolation & purification
  • Phytosterols / chemistry*
  • Phytosterols / isolation & purification
  • Plant Extracts / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Flavonoids
  • Phytochemicals
  • Phytosterols
  • Plant Extracts