DJ-1-mediated upregulation of serine palmitoyltransferase 2 controls vascular neointima via S1P autocrine

Int J Cardiol. 2015 Jul 15:191:220-2. doi: 10.1016/j.ijcard.2015.05.032. Epub 2015 May 8.

Authors

Kang Pa Lee¹, Kyung Jong Won¹, Dong Hyen Lee¹, Dong-Youb Lee¹, Seung Hyo Jung¹, Suji Baek¹, Tae-Sik Park², Bokyung Kim³

Affiliations

¹ Department of Physiology, Konkuk University, School of Medicine, Seoul 143-701, Republic of Korea.
² Department of Life Science, Gachon University, Seongnam 461-701, Republic of Korea.
³ Department of Physiology, Konkuk University, School of Medicine, Seoul 143-701, Republic of Korea. Electronic address: bkkim2@kku.ac.kr.

PMID: 25978603
DOI: 10.1016/j.ijcard.2015.05.032

No abstract available

Keywords: DJ-1; S1P autocrine; Vascular neointima.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Autocrine Communication / physiology*
Cell Movement / physiology
Lysophospholipids / biosynthesis*
Male
Mice
Mice, Knockout
Muscle, Smooth, Vascular / cytology
Muscle, Smooth, Vascular / metabolism
Neointima / metabolism*
Oncogene Proteins / physiology*
Peroxiredoxins / physiology*
Protein Deglycase DJ-1
Serine C-Palmitoyltransferase / biosynthesis*
Sphingosine / analogs & derivatives*
Sphingosine / biosynthesis
Up-Regulation / physiology*

Substances

Lysophospholipids
Oncogene Proteins
sphingosine 1-phosphate
Peroxiredoxins
Serine C-Palmitoyltransferase
PARK7 protein, mouse
Protein Deglycase DJ-1
Sphingosine