False-positive HIV test results in infancy and management of uninfected children receiving antiretroviral therapy

Pediatr Infect Dis J. 2015 Jun;34(6):607-9. doi: 10.1097/INF.0000000000000684.

Abstract

This report summarizes 2 children misdiagnosed with HIV infection in a clinic in rural Zambia and discusses the implications of false-positive HIV DNA tests in HIV-exposed infants, including the potential magnitude of the problem. Recommendations are needed to address the management of children receiving antiretroviral therapy who are suspected of being uninfected.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Retroviral Agents / therapeutic use*
  • Child, Preschool
  • Diagnostic Tests, Routine / methods*
  • False Positive Reactions*
  • Female
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pregnancy
  • Zambia

Substances

  • Anti-Retroviral Agents