Langerhans cell histiocytosis in monozygotic twins with central diabetes insipidus and hypophyseal masses

Sung-Tai Wei; Der-Cherng Chen; Der-Yang Cho; Hung-Lin Lin

doi:10.4103/1793-5482.145177

Langerhans cell histiocytosis in monozygotic twins with central diabetes insipidus and hypophyseal masses

Asian J Neurosurg. 2015 Apr-Jun;10(2):105-7. doi: 10.4103/1793-5482.145177.

Authors

Sung-Tai Wei¹, Der-Cherng Chen¹, Der-Yang Cho², Hung-Lin Lin¹

Affiliations

¹ Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C.
² Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C ; Graduate Institute of Immunology, China Medical University, Taichung, Taiwan, R.O.C.

Abstract

Langerhans cell histiocytosis (LCH) is a systemic disease mainly affecting children and young adults. It can manifest as single system disorder or multi-system involvement. When the central nervous system is involved, the hypothalamic-pituitary axis is the most common location affected. Herein we report a rare case of Langerhans cell histiocytosis in monozygotic twins both with central diabetes and hypophyseal masses. This is the first report about LCH in monozygotic twins with hypophyseal lesions.

Keywords: Diabetes insipidus; infundibulum; langerhans cell histiocytosis; twins.

Publication types

Case Reports