When antimicrobial peptides hit the wrong target: a novel link between tumour macrophages and cancer stem cells

Gut. 2015 Dec;64(12):1841-2. doi: 10.1136/gutjnl-2015-309605. Epub 2015 May 12.

Authors

Giuseppe R Diaferia¹, Gioacchino Natoli¹

Affiliation

¹ Department of Experimental Oncology, European Institute of Oncology (IEO), Milan, Italy.

PMID: 25966994
DOI: 10.1136/gutjnl-2015-309605

No abstract available

Keywords: INFLAMMATION; MACROPHAGES; PANCREATIC CANCER; STEM CELLS.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Antimicrobial Cationic Peptides / metabolism*
Carcinoma, Pancreatic Ductal / metabolism*
Carcinoma, Pancreatic Ductal / pathology*
Humans
Neoplastic Stem Cells / metabolism*
Pancreatic Neoplasms / metabolism*
Pancreatic Neoplasms / pathology*
Tumor Microenvironment*

Substances

Antimicrobial Cationic Peptides